Search on: TRYPTOPHAN HYDROXYLASE 
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Descriptor English:   Tryptophan Hydroxylase 
Descriptor Spanish:   Triptófano Hidroxilasa 
Descriptor Portuguese:   Triptofano Hidroxilase 
Synonyms English:   Hydroxylase, Tryptophan
Monooxygenase, Tryptophan
Tryptophan Monooxygenase  
Tree Number:   D08.811.682.690.708.870
Definition English:   An enzyme that catalyzes the hydroxylation of TRYPTOPHAN to 5-HYDROXYTRYPTOPHAN in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of SEROTONIN. 
See Related English:   Tryptophan Oxygenase
 
History Note English:   78(73); was see under HYDROXYLASES 1975-77 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   14767 
Unique Identifier:   D014365 

Occurrence in VHL:
 

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